First version of quality handling (not working yet) and now it is

checked that a column is writable before enlarging it
This commit is contained in:
Celine Mercier
2016-05-11 16:38:14 +02:00
parent b3c47809da
commit 8ae7644945
8 changed files with 540 additions and 8 deletions

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@ -587,7 +587,7 @@ OBIDMS_column_p obi_create_column(OBIDMS_p dms,
}
// Build the indexer name if needed
if ((data_type == OBI_STR) || (data_type == OBI_SEQ))
if ((data_type == OBI_STR) || (data_type == OBI_SEQ) || (data_type == OBI_QUAL))
{
if (strcmp(indexer_name, "") == 0)
{
@ -603,7 +603,7 @@ OBIDMS_column_p obi_create_column(OBIDMS_p dms,
}
returned_data_type = data_type;
if ((data_type == OBI_STR) || (data_type == OBI_SEQ))
if ((data_type == OBI_STR) || (data_type == OBI_SEQ) || (data_type == OBI_QUAL))
// stored data is indices referring to data stored elsewhere
stored_data_type = OBI_IDX;
else
@ -750,8 +750,8 @@ OBIDMS_column_p obi_create_column(OBIDMS_p dms,
if (comments != NULL)
strncpy(header->comments, comments, COMMENTS_MAX_LENGTH);
// If the data type is OBI_STR or OBI_SEQ, the associated obi_indexer is opened or created
if ((returned_data_type == OBI_STR) || (returned_data_type == OBI_SEQ))
// If the data type is OBI_STR, OBI_SEQ or OBI_QUAL, the associated obi_indexer is opened or created
if ((returned_data_type == OBI_STR) || (returned_data_type == OBI_SEQ) || (returned_data_type == OBI_QUAL))
{
new_column->indexer = obi_indexer(dms, final_indexer_name);
if (new_column->indexer == NULL)
@ -900,8 +900,8 @@ OBIDMS_column_p obi_open_column(OBIDMS_p dms,
column->writable = false;
// If the data type is OBI_STR or OBI_SEQ, the associated indexer is opened
if (((column->header)->returned_data_type == OBI_STR) || ((column->header)->returned_data_type == OBI_SEQ))
// If the data type is OBI_STR, OBI_SEQ or OBI_QUAL, the associated indexer is opened
if (((column->header)->returned_data_type == OBI_STR) || ((column->header)->returned_data_type == OBI_SEQ) || ((column->header)->returned_data_type == OBI_QUAL))
{
column->indexer = obi_open_indexer(dms, (column->header)->indexer_name);
if (column->indexer == NULL)
@ -1028,8 +1028,8 @@ int obi_close_column(OBIDMS_column_p column)
// Close column directory if it was the last column opened from that directory
close_dir = obi_dms_is_column_name_in_list(column->dms, (column->header)->name);
// If the data type is OBI_STR or OBI_SEQ, the associated indexer is closed
if (((column->header)->returned_data_type == OBI_STR) || ((column->header)->returned_data_type == OBI_SEQ))
// If the data type is OBI_STR, OBI_SEQ or OBI_QUAL, the associated indexer is closed
if (((column->header)->returned_data_type == OBI_STR) || ((column->header)->returned_data_type == OBI_SEQ) || ((column->header)->returned_data_type == OBI_QUAL))
if (obi_close_indexer(column->indexer) < 0)
ret_val = -1;
@ -1155,6 +1155,14 @@ int obi_enlarge_column(OBIDMS_column_p column)
int column_file_descriptor;
char* column_file_name;
// Check if the column is read-only
if (!(column->writable))
{
obi_set_errno(OBICOL_UNKNOWN_ERROR);
obidebug(1, "\nError trying to enlarge a read-only column");
return -1;
}
// Get the column file name
column_file_name = build_column_file_name((column->header)->name, (column->header)->version);
if (column_file_name == NULL)
@ -1274,6 +1282,12 @@ void obi_ini_to_NA_values(OBIDMS_column_p column,
}
break;
case OBI_QUAL: for (i=start;i<end;i++)
{
*(((index_t*) (column->data)) + i) = OBIIdx_NA;
}
break;
case OBI_STR: for (i=start;i<end;i++)
{
*(((index_t*) (column->data)) + i) = OBIIdx_NA;

115
src/obidmscolumn_qual.c Normal file
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@ -0,0 +1,115 @@
/****************************************************************************
* OBIDMS_column_qual functions *
****************************************************************************/
/**
* @file obidsmcolumn_qual.c
* @author Celine Mercier
* @date May 4th 2016
* @brief Functions handling OBIColumns containing data in the form of indices referring to sequence quality arrays.
*/
#include <stdlib.h>
#include <stdio.h>
#include <stdint.h>
#include "obidmscolumn.h"
#include "obitypes.h"
#include "obidmscolumn_str.c"
/**********************************************************************
*
* D E F I N I T I O N O F T H E P U B L I C F U N C T I O N S
*
**********************************************************************/
int obi_column_set_obiqual_char_with_elt_idx(OBIDMS_column_p column, index_t line_nb, index_t element_idx, const char* value)
{ // TODO discuss
return obi_column_set_obistr_with_elt_idx(column, line_nb, element_idx, value);
}
int obi_column_set_obiqual_int_with_elt_idx(OBIDMS_column_p column, index_t line_nb, index_t element_idx, const uint8_t* value)
{
char* value_char;
// Transform the int array into a char array
// Length??
//value_char = ;
obi_column_set_obiqual_char_with_elt_idx(column, line_nb, element_idx, value_char)
return 0;
}
char* obi_column_get_obiqual_char_with_elt_idx(OBIDMS_column_p column, index_t line_nb, index_t element_idx)
{ // TODO discuss
char* value;
value = obi_column_get_obistr_with_elt_idx(column, line_nb, element_idx);
if (strcmp(value, OBIStr_NA) == 0)
return OBIQual_char_NA;
return value;
}
uint8_t* obi_column_get_obiqual_int_with_elt_idx(OBIDMS_column_p column, index_t line_nb, index_t element_idx) // TODO const? (mapped)
{
index_t idx;
if (obi_column_prepare_to_get_value(column, line_nb) < 0)
return OBIQual_int_NA;
idx = *(((index_t*) (column->data)) + (line_nb * ((column->header)->nb_elements_per_line)) + element_idx);
// Check NA
if (idx == OBIIdx_NA)
return OBIQual_int_NA;
return obi_retrieve_quality_int(column->indexer, idx);
}
int obi_column_set_obiqual_char_with_elt_name(OBIDMS_column_p column, index_t line_nb, const char* element_name, const char* value)
{
index_t element_idx = obi_column_get_element_index_from_name(column, element_name);
if (element_idx == OBIIdx_NA)
return -1;
return obi_column_set_obiqual_char_with_elt_idx(column, line_nb, element_idx, value);
}
int obi_column_set_obiqual_int_with_elt_name(OBIDMS_column_p column, index_t line_nb, const char* element_name, uint8_t* value)
{
index_t element_idx = obi_column_get_element_index_from_name(column, element_name);
if (element_idx == OBIIdx_NA)
return -1;
return obi_column_set_obiqual_int_with_elt_idx(column, line_nb, element_idx, value);
}
char* obi_column_get_obiqual_char_with_elt_name(OBIDMS_column_p column, index_t line_nb, const char* element_name)
{
index_t element_idx = obi_column_get_element_index_from_name(column, element_name);
if (element_idx == OBIIdx_NA)
return OBIQual_char_NA;
return obi_column_get_obiqual_char_with_elt_idx(column, line_nb, element_idx);
}
uint8_t* obi_column_get_obiqual_int_with_elt_name(OBIDMS_column_p column, index_t line_nb, const char* element_name) // TODO const? (mapped)
{
index_t element_idx = obi_column_get_element_index_from_name(column, element_name);
if (element_idx == OBIIdx_NA)
return OBIQual_int_NA;
return obi_column_get_obiqual_int_with_elt_idx(column, line_nb, element_idx);
}

194
src/obidmscolumn_qual.h Normal file
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@ -0,0 +1,194 @@
/****************************************************************************
* OBIDMS_column_qual header file *
****************************************************************************/
/**
* @file obidsmcolumn_qual.h
* @author Celine Mercier
* @date May 4th 2016
* @brief Header file for the functions handling OBIColumns containing data in the form of indices referring to sequence quality arrays.
*/
#ifndef OBIDMSCOLUMN_QUAL_H_
#define OBIDMSCOLUMN_QUAL_H_
#include <stdlib.h>
#include <stdio.h>
#include <stdint.h>
#include "obidmscolumn.h"
#include "obitypes.h"
/**
* @brief Sets a value in an OBIDMS column containing data in the form of indices referring
* to sequence qualities handled by an indexer, and using the index of the element in the column's line.
*
* This function is for qualities in the character string format.
*
* @warning Pointers returned by obi_open_column() don't allow writing.
*
* @param column A pointer as returned by obi_create_column() or obi_clone_column().
* @param line_nb The number of the line where the value should be set.
* @param element_idx The index of the element that should be set in the line.
* @param value The value that should be set, in the character string format.
*
* @returns An integer value indicating the success of the operation.
* @retval 0 on success.
* @retval -1 if an error occurred.
*
* @since May 2016
* @author Celine Mercier (celine.mercier@metabarcoding.org)
*/
int obi_column_set_obiqual_char_with_elt_idx(OBIDMS_column_p column, index_t line_nb, index_t element_idx, const char* value);
/**
* @brief Sets a value in an OBIDMS column containing data in the form of indices referring
* to sequence qualities handled by an indexer, and using the index of the element in the column's line.
*
* This function is for qualities in the integer format.
*
* @warning Pointers returned by obi_open_column() don't allow writing.
*
* @param column A pointer as returned by obi_create_column() or obi_clone_column().
* @param line_nb The number of the line where the value should be set.
* @param element_idx The index of the element that should be set in the line.
* @param value The value that should be set, in the integer format.
*
* @returns An integer value indicating the success of the operation.
* @retval 0 on success.
* @retval -1 if an error occurred.
*
* @since May 2016
* @author Celine Mercier (celine.mercier@metabarcoding.org)
*/
int obi_column_set_obiqual_int_with_elt_idx(OBIDMS_column_p column, index_t line_nb, index_t element_idx, uint8_t* value);
/**
* @brief Recovers a value in an OBIDMS column containing data in the form of indices referring
* to sequence qualities handled by an indexer, and using the index of the element in the column's line.
*
* This function returns quality scores in the character string format.
*
* @param column A pointer as returned by obi_create_column().
* @param line_nb The number of the line where the value should be recovered.
* @param element_idx The index of the element that should be recovered in the line.
*
* @returns The recovered value, in the character string format.
* @retval OBIQual_NA the NA value of the type if an error occurred and obi_errno is set.
*
* @since May 2016
* @author Celine Mercier (celine.mercier@metabarcoding.org)
*/
char* obi_column_get_obiqual_char_with_elt_idx(OBIDMS_column_p column, index_t line_nb, index_t element_idx);
/**
* @brief Recovers a value in an OBIDMS column containing data in the form of indices referring
* to sequence qualities handled by an indexer, and using the index of the element in the column's line.
*
* This function returns quality scores in the integer format.
*
* @param column A pointer as returned by obi_create_column().
* @param line_nb The number of the line where the value should be recovered.
* @param element_idx The index of the element that should be recovered in the line.
*
* @returns The recovered value, in the integer format.
* @retval OBIQual_NA the NA value of the type if an error occurred and obi_errno is set.
*
* @since May 2016
* @author Celine Mercier (celine.mercier@metabarcoding.org)
*/
uint8_t* obi_column_get_obiqual_int_with_elt_idx(OBIDMS_column_p column, index_t line_nb, index_t element_idx);
/**
* @brief Sets a value in an OBIDMS column containing data in the form of indices referring
* to sequence qualities handled by an indexer, and using the index of the element in the column's line.
*
* This function is for quality scores in the character string format.
*
* @warning Pointers returned by obi_open_column() don't allow writing.
*
* @param column A pointer as returned by obi_create_column() or obi_clone_column().
* @param line_nb The number of the line where the value should be set.
* @param element_name The name of the element that should be set in the line.
* @param value The value that should be set, in the character string format.
*
* @returns An integer value indicating the success of the operation.
* @retval 0 on success.
* @retval -1 if an error occurred.
*
* @since May 2016
* @author Celine Mercier (celine.mercier@metabarcoding.org)
*/
int obi_column_set_obiqual_char_with_elt_name(OBIDMS_column_p column, index_t line_nb, const char* element_name, const char* value);
/**
* @brief Sets a value in an OBIDMS column containing data in the form of indices referring
* to sequence qualities handled by an indexer, and using the index of the element in the column's line.
*
* This function is for quality scores in the integer format.
*
* @warning Pointers returned by obi_open_column() don't allow writing.
*
* @param column A pointer as returned by obi_create_column() or obi_clone_column().
* @param line_nb The number of the line where the value should be set.
* @param element_name The name of the element that should be set in the line.
* @param value The value that should be set, in the integer format.
*
* @returns An integer value indicating the success of the operation.
* @retval 0 on success.
* @retval -1 if an error occurred.
*
* @since May 2016
* @author Celine Mercier (celine.mercier@metabarcoding.org)
*/
int obi_column_set_obiqual_int_with_elt_name(OBIDMS_column_p column, index_t line_nb, const char* element_name, uint8_t* value);
/**
* @brief Recovers a value in an OBIDMS column containing data in the form of indices referring
* to sequence qualities handled by an indexer, and using the index of the element in the column's line.
*
* This function returns quality scores in the character string format.
*
* @param column A pointer as returned by obi_create_column() or obi_clone_column().
* @param line_nb The number of the line where the value should be recovered.
* @param element_name The name of the element that should be recovered in the line.
*
* @returns The recovered value, in the character string format.
* @retval OBIQual_NA the NA value of the type if an error occurred and obi_errno is set.
*
* @since May 2016
* @author Celine Mercier (celine.mercier@metabarcoding.org)
*/
char* obi_column_get_obiqual_char_with_elt_name(OBIDMS_column_p column, index_t line_nb, const char* element_name);
/**
* @brief Recovers a value in an OBIDMS column containing data in the form of indices referring
* to sequence qualities handled by an indexer, and using the index of the element in the column's line.
*
* This function returns quality scores in the integer format.
*
* @param column A pointer as returned by obi_create_column() or obi_clone_column().
* @param line_nb The number of the line where the value should be recovered.
* @param element_name The name of the element that should be recovered in the line.
*
* @returns The recovered value, in the integer format.
* @retval OBIQual_NA the NA value of the type if an error occurred and obi_errno is set.
*
* @since May 2016
* @author Celine Mercier (celine.mercier@metabarcoding.org)
*/
utin8_t* obi_column_get_obiqual_int_with_elt_name(OBIDMS_column_p column, index_t line_nb, const char* element_name);
#endif /* OBIDMSCOLUMN_QUAL_H_ */

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@ -28,6 +28,17 @@ int obi_column_set_obistr_with_elt_idx(OBIDMS_column_p column, index_t line_nb,
{
index_t idx;
// TODO
// size_t i;
// uint8_t q;
// for (i=0;i<=strlen(value);i++)
// {
// if ()
// q = ((uint8_t) value[i]) - 33;
// fprintf(stderr, "\n%c == %u", value[i], q);
// }
if (obi_column_prepare_to_set_value(column, line_nb) < 0)
return -1;

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@ -40,6 +40,9 @@ size_t obi_sizeof(OBIType_t type)
case OBI_CHAR: size = sizeof(obichar_t);
break;
case OBI_QUAL: size = sizeof(index_t);
break;
case OBI_STR: size = sizeof(index_t);
break;
@ -96,6 +99,9 @@ char* name_data_type(int data_type)
case OBI_CHAR: name = strdup("OBI_CHAR");
break;
case OBI_QUAL: name = strdup("OBI_QUAL");
break;
case OBI_STR: name = strdup("OBI_STR");
break;

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@ -24,6 +24,8 @@
#define OBIChar_NA (0) /**< NA value for the type OBI_CHAR */ // TODO not sure about this one as it can be impossible to distinguish from uninitialized values
#define OBISeq_NA ("\0") /**< NA value for the type OBI_SEQ */ // TODO discuss
#define OBIStr_NA ("\0") /**< NA value for the type OBI_STR */ // TODO discuss
#define OBIQual_char_NA ("\0") /**< NA value for the type OBI_QUAL if the quality is in character string format */ // TODO test and discuss
#define OBIQual_int_NA ("\0") /**< NA value for the type OBI_QUAL if the quality is in integer format */ // TODO test and discuss
/**
@ -45,6 +47,7 @@ typedef enum OBIType {
OBI_FLOAT, /**< a floating value (C type : double) */
OBI_BOOL, /**< a boolean true/false value, see obibool_t enum */
OBI_CHAR, /**< a character (C type : char) */
OBI_QUAL, /**< an index in a data structure (C type : int64_t) referring to a quality score array */
OBI_STR, /**< an index in a data structure (C type : int64_t) referring to a character string */
OBI_SEQ, /**< an index in a data structure (C type : int64_t) referring to a DNA sequence */
OBI_IDX /**< an index referring to a line in another column (C type : int64_t) */

102
src/uint8_indexer.c Normal file
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@ -0,0 +1,102 @@
/****************************************************************************
* Sequence quality scores indexing functions *
****************************************************************************/
/**
* @file quality_indexer.c
* @author Celine Mercier
* @date May 4th 2016
* @brief Functions handling the indexing and retrieval of sequence quality scores.
*/
#include <stdlib.h>
#include <stdio.h>
#include <math.h>
#include "obiblob.h"
#include "obiblob_indexer.h"
#include "obidebug.h"
#include "obitypes.h"
#define DEBUG_LEVEL 0 // TODO has to be defined somewhere else (cython compil flag?)
Obi_blob_p obi_uint8_to_blob(const char* quality)
{
Obi_blob_p value_b;
int32_t length_encoded_seq; // length of the encoded sequence in bytes
int32_t seq_length;
byte_t* encoded_seq;
seq_length = strlen(seq);
// Check if just ATGC and encode accordingly
if (only_ATGC(seq))
{
// Compute the length (in bytes) of the encoded sequence
length_encoded_seq = ceil((double) seq_length / (double) 4.0);
// Encode
encoded_seq = encode_seq_on_2_bits(seq, seq_length);
if (encoded_seq == NULL)
return NULL;
value_b = obi_blob(encoded_seq, ELEMENT_SIZE_SEQ_2, length_encoded_seq, seq_length);
}
else
{
// Compute the length (in bytes) of the encoded sequence
length_encoded_seq = ceil((double) seq_length / (double) 2.0);
// Encode
encoded_seq = encode_seq_on_4_bits(seq, seq_length);
if (encoded_seq == NULL)
return NULL;
value_b = obi_blob(encoded_seq, ELEMENT_SIZE_SEQ_4, length_encoded_seq, seq_length);
}
free(encoded_seq);
return value_b;
}
char* obi_blob_to_quality_char(Obi_blob_p value_b)
{
// Decode
if (value_b->element_size == 2)
return decode_seq_on_2_bits(value_b->value, value_b->length_decoded_value);
else
return decode_seq_on_4_bits(value_b->value, value_b->length_decoded_value);
}
index_t obi_index_quality_char(Obi_indexer_p indexer, const char* value)
{
Obi_blob_p value_b;
index_t idx;
// Encode value
value_b = obi_seq_to_blob(value);
if (value_b == NULL)
return -1;
// Add in the indexer
idx = obi_indexer_add(indexer, value_b);
free(value_b);
return idx;
}
char* obi_retrieve_dna_seq(Obi_indexer_p indexer, index_t idx)
{
Obi_blob_p value_b;
// Get encoded value
value_b = obi_indexer_get(indexer, idx);
// Return decoded sequence
return obi_blob_to_seq(value_b);
}

87
src/uint8_indexer.h Normal file
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@ -0,0 +1,87 @@
/****************************************************************************
* DNA sequence indexer header file *
****************************************************************************/
/**
* @file dna_seq_indexer.h
* @author Celine Mercier
* @date April 12th 2016
* @brief Header file for the functions handling the indexing of DNA sequences.
*/
#ifndef DNA_SEQ_INDEXER_H_
#define DNA_SEQ_INDEXER_H_
#include <stdlib.h>
#include <stdio.h>
#include "obidms.h"
#include "obitypes.h"
#include "obiblob.h"
#include "obiblob_indexer.h"
/**
* @brief Converts a DNA sequence to a blob.
*
* @warning The blob must be freed by the caller.
*
* @param value The DNA sequence to convert.
*
* @returns A pointer to the blob created.
* @retval NULL if an error occurred.
*
* @since November 2015
* @author Celine Mercier (celine.mercier@metabarcoding.org)
*/
Obi_blob_p obi_seq_to_blob(const char* seq);
/**
* @brief Converts a blob to a DNA sequence.
*
* @param value_b The blob to convert.
*
* @returns A pointer to the DNA sequence contained in the blob.
* @retval NULL if an error occurred.
*
* @since November 2015
* @author Celine Mercier (celine.mercier@metabarcoding.org)
*/
char* obi_blob_to_seq(Obi_blob_p value_b);
/**
* @brief Stores a DNA sequence in an indexer and returns the index.
*
* @param indexer The indexer structure.
* @param value The DNA sequence to index.
*
* @returns The index referring to the stored DNA sequence in the indexer.
*
* @since April 2016
* @author Celine Mercier (celine.mercier@metabarcoding.org)
*/
index_t obi_index_dna_seq(Obi_indexer_p indexer, const char* value);
/**
* @brief Retrieves a DNA sequence from an indexer.
*
* @warning The DNA sequence returned must be freed by the caller.
*
* @param indexer The indexer structure.
* @param idx The index referring to the DNA sequence to retrieve in the indexer.
*
* @returns A pointer on the DNA sequence.
*
* @since April 2016
* @author Celine Mercier (celine.mercier@metabarcoding.org)
*/
char* obi_retrieve_dna_seq(Obi_indexer_p indexer, index_t idx);
#endif /* DNA_SEQ_INDEXER_H_ */