mirror of
https://github.com/metabarcoding/obitools4.git
synced 2025-06-29 16:20:46 +00:00
101 lines
2.1 KiB
Go
101 lines
2.1 KiB
Go
package obialign
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import (
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"math"
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)
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var _FourBitsCount = []float64{
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0, // 0000
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1, // 0001
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1, // 0010
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2, // 0011
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1, // 0100
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2, // 0101
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2, // 0110
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3, // 0111
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1, // 1000
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2, // 1001
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2, // 1010
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3, // 1011
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2, // 1100
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3, // 1101
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3, // 1110
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4, // 1111
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}
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var _InitializedDnaScore = false
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var _NucPartMatch [32][32]float64
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var _NucScorePartMatchMatch [100][100]int
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var _NucScorePartMatchMismatch [100][100]int
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func _MatchRatio(a, b byte) float64 {
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// count of common bits
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cm := _FourBitsCount[a&b&15]
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ca := _FourBitsCount[a&15]
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cb := _FourBitsCount[b&15]
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if cm == 0 || ca == 0 || cb == 0 {
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return float64(0)
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}
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return float64(cm) / float64(ca) / float64(cb)
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}
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func _Logaddexp(a, b float64) float64 {
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if a > b {
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a, b = b, a
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}
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return b + math.Log1p(math.Exp(a-b))
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}
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func _MatchScoreRatio(a, b byte) (float64, float64) {
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l2 := math.Log(2)
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l3 := math.Log(3)
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l10 := math.Log(10)
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lalea := math.Log(30) // 1 /(change of the random model)
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lE1 := -float64(a)/10*l10 - l3 // log proba of sequencing error on A/3
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lE2 := -float64(b)/10*l10 - l3 // log proba of sequencing error on B/3
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lO1 := math.Log1p(-math.Exp(lE1 + l3)) // log proba no being an error on A
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lO2 := math.Log1p(-math.Exp(lE2 + l3)) // log proba no being an error on B
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lO1O2 := lO1 + lO2
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lE1E2 := lE1 + lE2
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lO1E2 := lO1 + lE2
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lO2E1 := lO2 + lE1
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MM := _Logaddexp(lO1O2, lE1E2+l3) // Proba match when match observed
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Mm := _Logaddexp(_Logaddexp(lO1E2, lO2E1), lE1E2+l2) // Proba match when mismatch observed
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return MM + lalea, Mm + lalea
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}
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func _InitNucPartMatch() {
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for i, a := range _FourBitsBaseCode {
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for j, b := range _FourBitsBaseCode {
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_NucPartMatch[i][j] = _MatchRatio(a, b)
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}
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}
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}
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func _InitNucScorePartMatch() {
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for i := 0; i < 100; i++ {
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for j := 0; j < 100; j++ {
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MM, Mm := _MatchScoreRatio(byte(i), byte(j))
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_NucScorePartMatchMatch[i][j] = int(MM*10 + 0.5)
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_NucScorePartMatchMismatch[i][j] = int(Mm*10 + 0.5)
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}
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}
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}
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func _InitDNAScoreMatrix() {
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if !_InitializedDnaScore {
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_InitNucPartMatch()
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_InitNucScorePartMatch()
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_InitializedDnaScore = true
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}
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}
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