2.6 KiB
MPHF selection — analysis in progress
The choice of Minimal Perfect Hash Function for phase 6 is not yet settled. Three candidates were evaluated.
Candidates
boomphf (BBHash algorithm, maintained by 10X Genomics):
- ~3.7 bits/key; mature crate, used in production bioinformatics (Pufferfish, Piscem)
- Parallel construction; well-tested with DNA kmer data at scale
- Drawback: largest space footprint of the three
ptr_hash (PtrHash algorithm, Groot Koerkamp, SEA 2025):
- ~2.4 bits/key; fastest queries (≥2.1× over alternatives, 8–12 ns/key for u64 in tight loops) and fastest construction (≥3.1×)
- Theoretical foundation solid; paper and Rust crate from the same author
- Drawback: published February 2025 — very young, no production track record
FMPHGO (ph crate, Beling, ACM JEA 2023):
- ~2.1 bits/key — most compact of the three; good query speed; parallelisable construction
- More established than ptr_hash; actively maintained
- Currently preferred candidate
Space at scale
For 1 024 partitions × 100 M kmers/partition:
| MPHF | bits/key | Total MPHF size |
|---|---|---|
| boomphf | 3.7 | ~47 GB |
| ptr_hash | 2.4 | ~31 GB |
| FMPHGO | 2.1 | ~27 GB |
In practice, partition sizes depend on the dataset. For a human genome at 30× coverage with p=10 (1 024 partitions), realistic partition sizes are 3–30 M kmers → 1–8 MB per MPHF, well within RAM.
On-disk and mmap considerations
All three are in-memory structures. Their internal representation is flat bit arrays (no heap pointers), making them serialisable as contiguous byte blobs and mmappable per partition. True zero-copy access would require rkyv integration; the ph crate currently uses serde, so loading involves a copy. Given per-partition MPHF sizes of 1–8 MB, the OS page cache handles this transparently — strict zero-copy is a refinement, not a blocker.
No established Rust crate provides a natively on-disk MPHF. SSHash (Sparse and Skew Hash) is a complete kmer dictionary designed for disk access and is order-preserving (overlapping kmers receive consecutive indices → cache-friendly count access), but it is C++-only and covers more than just the MPHF layer.
Open questions
- Confirm actual partition sizes on representative metagenomic datasets before fixing the choice.
- Evaluate whether ptr_hash's query speed advantage (2.1–3.3×) justifies adopting a crate that is less than a year old.
- Assess rkyv integration cost for FMPHGO if true zero-copy mmap becomes necessary.
- Keep SSHash in mind if the indexing architecture is reconsidered at a higher level.