⬆️ version bump to v4.5

- Update obioptions.Version from "Release 4.4.29" to "/v/ Release v5"
- Update version.txt from 4.29 → .30
(automated by Makefile)

autodoc/docmd/pkg/obiseq/revcomp.md

@@ -0,0 +1,35 @@
+# BioSequence Reverse Complement Functionality
+
+This Go package (`obiseq`) provides utilities for computing the reverse complement of biological sequences (e.g., DNA), including support for quality scores and structured metadata.
+
+## Core Functions
+
+- **`nucComplement(n byte) byte`**  
+  Returns the nucleotide complement using a lookup table (`_revcmpDNA`). Handles special cases:  
+  - `.` / `-` → unchanged (gaps)  
+  - `[`, `]` → swapped (`[` ↔ `]`)  
+  - A–Z letters → complemented (case-insensitive via bitwise masking)  
+  - Unknown characters → `'n'`
+
+- **`BioSequence.ReverseComplement(inplace bool) *BioSequence`**  
+  Performs reverse complement on the sequence and (if present) its quality string:  
+  - If `inplace = false`, a copy is made; original preserved.  
+  - Reverses indices and complements each base using `nucComplement`.  
+  - Also reverses the quality array symmetrically.  
+  - Caches result in `sequence.revcomp` for reuse.
+
+- **`BioSequence._revcmpMutation() *BioSequence`**  
+  Adjusts mutation metadata (e.g., `"pairing_mismatches"`) to reflect the reversed-complement orientation:  
+  - Reverses and complements symbolic mutation strings (e.g., `"A>T"` → `"T>A"`).  
+  - Updates positional indices to match reversed sequence coordinates.
+
+- **`ReverseComplementWorker(inplace bool) SeqWorker`**  
+  Returns a reusable `SeqWorker` function for batch processing: applies reverse complement to each sequence in a stream.
+
+## Design Notes
+
+- Uses ASCII bitwise tricks (`&31`, `|0x20`) for case-insensitive indexing and lowercase output.  
+- Supports non-standard symbols (e.g., IUPAC ambiguity codes via lookup table).  
+- Integrates quality scores and structured attributes seamlessly.  
+
+> Ideal for NGS preprocessing pipelines where orientation matters (e.g., paired-end alignment, variant calling).