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Patch an aligment bug on obipairing

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This commit is contained in:
Eric Coissac
2023-01-25 13:22:56 +01:00
parent 9b7edf0908
commit cfddc78161
4 changed files with 112 additions and 27 deletions
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16
pkg/obialign/dnamatrix.go
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@ -55,21 +55,21 @@ func _MatchScoreRatio(a, b byte) (float64, float64) {
l2 := math.Log(2)
l3 := math.Log(3)
l4 := math.Log(4)
l10 := math.Log(10)
lE1 := -float64(a)/10*l10 - l4
lE2 := -float64(b)/10*l10 - l4
lO1 := math.Log1p(-math.Exp(lE1 + l3))
lO2 := math.Log1p(-math.Exp(lE2 + l3))
lalea := math.Log(30) // 1 /(change of the random model)
lE1 := -float64(a)/10*l10 - l3 // log proba of sequencing error on A/3
lE2 := -float64(b)/10*l10 - l3 // log proba of sequencing error on B/3
lO1 := math.Log1p(-math.Exp(lE1 + l3)) // log proba no being an error on A
lO2 := math.Log1p(-math.Exp(lE2 + l3)) // log proba no being an error on B
lO1O2 := lO1 + lO2
lE1E2 := lE1 + lE2
lO1E2 := lO1 + lE2
lO2E1 := lO2 + lE1
MM := _Logaddexp(lO1O2, lE1E2+l3) + l4
Mm := _Logaddexp(_Logaddexp(lO1E2, lO2E1), lE1E2+l2) + l4
MM := _Logaddexp(lO1O2, lE1E2+l3) // Proba match when match observed
Mm := _Logaddexp(_Logaddexp(lO1E2, lO2E1), lE1E2+l2) // Proba match when mismatch observed
return MM, Mm
return MM + lalea, Mm + lalea
}
func _InitNucPartMatch() {